An Atlas of Osteoporosis, Third Edition by John C. Stevenson, Michael S. Marsh

By John C. Stevenson, Michael S. Marsh

The 3rd variation of this winning Atlas of Osteoporosis is designed to supply a variety of physicians with a pictorial consultant to this crucial ailment. The illustrations are a good instructing source and the textual content offers a concise evaluation to osteoporosis. For the 1st time, textual content and illustrations are totally built-in. The publication includes info of skeletal biology and the pathophysiology of osteoporosis, with a sequence of diagrammatic and SEM illustrations. there's higher emphasis on medical elements during this version, rather in parts reminiscent of food, workout, and development. There also are vital sections on analysis utilizing bone densitometry and the laboratory evaluate of bone problems.

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11. Moss DW, King EJ. Properties of alkaline phosphatase fractions separated by starch gel electrophoresis. Biochemistry 1962; 84: 192–5. 12. Posen S, Neale FC, Clubb JS. Heat inactivation in the study of human alkaline phosphatases. Ann Intern Med 1965; 62: 1234–43. 13. Christiansen C, Riis BJ. Risk assessment using biochemical analysis. In: Smith R, ed. Osteoporosis. London: Royal College of Physicians, 1990: 158–61. 14. Eftekharian MM, Moazzeni SM, Pourfathollah AA, Khabiri, AR. Production of monoclonal antibody against alkaline phosphatase.

44. Khosla S, Amighi HM, Melton LJ et al. Correlates of osteoprotegerin levels in women and men. Osteoporos Int 2002; 13: 394–9. 45. Khosla S, Riggs BL, Atkinson EJ et al. Relationship of estrogen receptor genotypes to bone mineral density and to rates of bone loss in men. J Clin Endocrinol Metab 2004; 89: 1808–16. 46. Syed F, Khosla S. Mechanisms of sex steroid effects on bone. Biochem Biophys Res Commun 2005; 328: 688–96. 34. Kalu DN, Salerno E, Higami Y et al. In vivo effects of transforming growth factor-beta 2 in ovariectomized rats.

In vivo effects of transforming growth factor-beta 2 in ovariectomized rats. Bone Miner 1993; 22: 209–20. 19 CHAPTER 3 Pathophysiology The major factors that determine whether a person develops osteoporosis are the maximum (peak) bone density that is achieved and the amount that is subsequently lost. Bone quality and architecture are also important. 2). The bone mass at skeletal maturity differs between the sexes, being 30–50% greater in men than in women3,4. However, the lean/bone mass ratios in mature men and women are similar, suggesting that both sexes at that time have an equal capacity to withstand mechanical trauma.

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